Table of Contents

ZYMOGENETICS INC filed this Form 8-K on May 4, 2010.

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Entire Document (8-K) PAGE 1. UNITED STATES PAGE 2. Item 2.02. PAGE 3. SIGNATURES PAGE 4. EXHIBIT INDEX

Entire Document (EX-99.1) PAGE 1. Exhibit 99.1 PAGE 2. Business Highlights PAGE 3. Interleukin-21 (IL-21, Phase 2) PAGE 4. Securities and Exchange Commission from time to time, including ZymoGenetics most recent Annual Rep PAGE 5. ZYMOGENETICS, INC.